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Understanding the Spread of Human Papillomavirus (HPV) in Sub-Saharan Africa: A Mathematical Modeling Approach

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Human Papillomavirus (HPV) is one of the most common sexually transmitted infections in the world and can lead to serious health issues such as cervical cancer. This thesis focuses on how HPV spreads, particularly in Sub-Saharan Africa, and explores various prevention strategies through a mathematical model.

The model developed in this study examines the impact of different ways to control the infection, such as preventive vaccination for young people and catch-up vaccination for adults. It takes into account not only sexual transmission but also indirect transmission through contaminated surfaces, which is often overlooked in traditional studies.

The results show that combining vaccination with environmental hygiene measures significantly reduces the spread of the virus. The study also highlights that targeted strategies, like vaccinating adults in addition to children, are especially effective.

This work provides a valuable mathematical framework to help policymakers improve public health strategies, particularly in resource-limited countries, and enhance efforts to control this infection.

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